Treatment Marble Bone Disease

The mass of bone increases but the new bone material.

Treatment marble bone disease. This means that the bone tissue is substantially sealed. Marble bone disease causes short stature cerebral calcification and mental retardation. Traditionally the disease has been recognized in two forms. In healthy individuals bones are constantly being broken down resorption by cells called osteoclasts and new bone material is constantly being formed by cells called osteoblasts.

Osteopetrosis marble bone disease osteopetrosis tarda albers schonberg disease. The marrow cavities become filled with compact bone. The disease progresses as long as bone growth continues. Marble bone disease when there is a failure in bone resorption.

Symptoms and severity can vary greatly ranging from neonatal onset with life threatening complications such as bone marrow failure to the incidental finding of osteopetrosis on x ray depending on severity and age of onset features may include fractures. Osteogenesis imperfecta congenita which is apparent at birth and osteogenesis imperfecta tarda which manifests itself usually in early childhood with milder. This condition in turn leads to bones getting dissolved and ultimately break. The most informative tool in determining the presence of marble disease is an x ray.

Introduction osteopetrosis is a disorder characterized by defective or absent osteoclasts the cells that resorb bone was first described in 1904 by heinrich albers schenberg. Because increased bone mass crowds the bone marrow resulting in a reduced amount of marrow. Marble this disease named for two reasons. Osteopetrosis or marble bone disease this is an extremely rare genetic disorder of the bones in which the bones get harder and denser.

The musculoskeletal system consists of the body s bones muscles tendons ligaments joints cartilage. Marble bone disease description causes and risk factors. Osteogenesis imperfecta or brittle bone disease is a group of hereditary connective tissue disorders characterized by unusual bone fragility and tendency to fracture. Marble bone disease rare disorder in which the bones become extremely dense hard and brittle.

Find diagnosis treatment and prevention information on more than 20 different muscle and bone diseases and conditions affecting the musculoskeletal system. Osteopetrosis refers to a group of rare inherited skeletal disorders characterized by increased bone density and abnormal bone growth.